Many cancer drugs remain unproven 5 years after accelerated approval, a study finds

The U.S. Food and Drug Administration’s accelerated approval program is meant to give patients early access to promising drugs. But how often do these drugs actually improve or extend patients’ lives? In a new study, researchers found that most cancer drugs granted accelerated approval do not demonstrate such benefits within five years. “Five years after … Read more

ALS drug will be pulled from US market after study showed patients didn’t benefit

WASHINGTON — The maker of a drug for Lou Gehrig’s disease that recently failed in a large study said Thursday it will pull the medicine from the market, acknowledging it didn’t help patients with the deadly neurological condition. Amylyx Pharmaceuticals announced it will voluntarily halt sales and marketing of the drug in the U.S. and … Read more

New study finds no brain injuries among ‘Havana syndrome’ patients

WASHINGTON — An array of advanced tests found no brain injuries or degeneration among U.S. diplomats and other government employees who suffer mysterious health problems once dubbed “Havana syndrome, ” researchers reported Monday. The National Institutes of Health’s nearly five-year study offers no explanation for symptoms including headaches, balance problems and difficulties with thinking and … Read more

FDA expands use of asthma drug Xolair to treat severe food allergies

A medication used to treat asthma can now be used to help people with food allergies avoid severe reactions, the U.S. Food and Drug Administration said Friday. Xolair, the brand name for the drug omalizumab, became the first medication approved to reduce allergic reactions caused by accidental exposure to food triggers. Patients as young as … Read more

The effect of police violence on Black Americans’ health documented in 2 new studies

The effect of police violence on Black Americans is tracked in two new studies, with one tying police-involved deaths to sleep disturbances and the other finding a racial gap in injuries involving police use of Tasers. The health effects of police violence on Black people “need to be documented as a critical first step to … Read more

As investors pile into psychedelics, idealism gives way to pharma economics

Money is pouring into the fledgling psychedelic medicine industry, with dozens of startup companies vying to be among the first to sell mind-expanding drugs for depression, addiction and other mental health conditions. While psychedelics are still illegal under federal law, companies are jostling to try and patent key ingredients found in magic mushrooms, ayahuasca and … Read more

Science sleuths are using technology to find fakery and plagiarism in published research

Allegations of research fakery at a leading cancer center have turned a spotlight on scientific integrity and the amateur sleuths uncovering image manipulation in published research. Dana-Farber Cancer Institute, a Harvard Medical School affiliate, announced Jan. 22 it’s requesting retractions and corrections of scientific papers after a British blogger flagged problems in early January. The … Read more

Ancient human DNA hints at why a modern disease affects so many northern Europeans today

WASHINGTON — Ancient DNA helps explain why northern Europeans have a higher risk of multiple sclerosis than other ancestries: It’s a genetic legacy of horseback-riding cattle herders who swept into the region about 5,000 years ago. The findings come from a huge project to compare modern DNA with that culled from ancient humans’ teeth and … Read more

Crib videos offer clue to mysterious child deaths, showing seizures sometimes play a role

The last bedtime of 17-month-old Hayden Fell’s life was heartbreakingly normal. Crib video shows the toddler in pajamas playing happily as his parents and sister sang “Wheels on the Bus” with his twin brother. The next morning, Hayden’s dad couldn’t wake him. The tot had become one of several hundred seemingly healthy U.S. toddlers and … Read more

US women stocking up on abortion pills, especially amid news about restrictions

Thousands of women stocked up on abortion pills just in case they needed them, new research shows, with demand peaking in the past couple years at times when it looked like the medications might become harder to get. Medication abortion accounts for more than half of all abortions in the U.S., and typically involves two … Read more